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This graph depicts the comparative remission rates at weeks 1, 2, 3, 4, 6, and 8 of treatment with placebo, SSRIs, or venlafaxine The difference between SSRIs and venlafaxine was evident as early as week 2 (P<0.005). Significantly higher remission rates also were observed at weeks 4, 6, and 8 for venlafaxine and for venlafaxine XR compared with the SSRIs The final remission rates for venlafaxine and SSRIs at endpoint was 45% vs 35%. This represents an increase in efficacy of approximately 30% (45% ¸ 35% = 1.29 » 30% increase)
Source:
Thase ME, et al. Br J Psychiatry. 2001;178:234-241.
Venlafaxine was significantly more effective in achieving remission compared with SSRIs from week 2 through 8
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